May 20^th, Sunday

13⁰⁰-17⁰⁰

Registration

17⁰⁰-17³⁰

Opening Ceremony

17³⁰-18¹⁰

Keynote Lecture

Her Royal Highness Professor Dr. Princess Chulabhorn Mahidol

Opportunities and challenges on environmental health in Southeast Asia.

President, Chulabhorn Research Institute, Bangkok, Thailand.

(Introduction by Semra Şardaş).

18³⁰-20³⁰

Welcome Reception

May 21^th, Monday

08³⁰-09¹⁰

Keynote Lecture

William Suk

Strategies for addressing global environmental health concerns. 

Director, Center for Risk and Integrated Sciences and Director, Superfund Basic Research Program, National Institute of Environmental Health Sciences, RTP,

North Carolina, USA. (Introduction by Ali E. Karakaya)

09¹⁰-09³⁰

Coffee Break

09³⁰-12⁰⁰

Symposium Session 1

Mechanisms of Mutagenesis and Carcinogenesis

Co-Chairs:

• David DeMarini, National Institute of Environmental Health Sciences, USA.
• Lucia Ribeiro, University of Sao Paolo, Brazil.

09³⁰-10⁰⁰

Lawrence Loeb:  Random mutations and human cancer. University of Washington, Seattle, WA, USA.

10⁰⁰-10³⁰

Alain Sarasin: DNA repair pathways and risk of metastasis in melanoma patients. CNRS, Villejuif, France.

10³⁰-11⁰⁰

Martina Viegl: DNA repair and epigenetic alterations in the development of colon cancer. Case Western Reserve University, Cleveland, OH, USA.. 

11⁰⁰-11³⁰

Bernd Kaina: Genotoxic and apoptotic responses triggered by DNA alkylation damage. University of Mainz, Mainz, Germany.

11³⁰-12⁰⁰

Eugenia Dogliotti: Mechanisms of oxidative DNA damage repair and relevance to human pathology. Istituto Superiore di Sanita, Rome, Italy.

12⁰⁰-13⁰⁰

Lunch

13⁰⁰-15³⁰

Symposium Session 2

Children Environmental Health

Co-Chairs:

• Nina Holland, University of California, Berkeley, USA.
• Wagida Anwar, Ain Shams University, Cairo, Egypt.

13⁰⁰-13³⁰

Stefano Bonassi:  Epidemiological study design in children’s studies.  National Cancer Research Institute, Genoa, Italy.

13³⁰-14⁰⁰

Christopher Wild:  Environmental exposures and child health in developing countries: The example of aflatoxin. Leeds University, England.

14⁰⁰-14³⁰

Alexandra Fucic: Genome damage in children after complex exposures to chemical and physical agents. Institute of Medical Research and Occupational Health, Croatia.

14³⁰-15⁰⁰

Semra Şardaş: General evaluation of child labour in Turkey and related genome studies. Marmara University, Istanbul, Turkey.

15⁰⁰-15³⁰

Nina Holland: Genetic and immunological biomarkers in children. University of California, Berkeley, California, USA.

15³⁰-15⁵⁰

Coffee Break

15⁵⁰-18²⁰

Symposium Session 3

Human Monitoring for Health Risk Evaluation and Disease Prevention

Co-Chairs:

• Silvio De Flora, University of Genoa, Genoa, Italy.
• Mathuros Ruchirawat, Princess Chulabhorn Research Institute, Bangkok, Thailand.

15⁵⁰-16²⁰

Peter Farmer: Use of biomarkers to identify health risk from exposure to hazardous environmental pollutants. Cancer Biomarkers and Prevention Group, Leicester, United Kingdom.        

16²⁰-16⁵⁰

Albrecht Seidel: Determination of urinary chemical metabolites for assessment of exposure of the general population to environmental toxic PAH. Biochemical Institute for Environmental Carcinogens.  Grosshansdorf, Germany.

16⁵⁰-17²⁰

Silvio De Flora: Threshold mechanisms for genotoxic carcinogens. The example of chromium(VI). University of Genoa, Genoa, Italy.

17²⁰-17⁵⁰

Ilse Decordier: On comparison of repair capacities in mothers and newborn daughters. Vrije Universiteit Brussel, Brussels, Belgium.

17⁵⁰-18²⁰

Young-Joon Surh: Inflammation-associated cancer and its chemoprevention. Seoul National University, Korea.

19⁰⁰-20³⁰

Dinner

20³⁰-22³⁰

Workshop 1

HUMN Project Workshop on the Buccal Micronucleus Assay

• Michael Fenech, CSIRO Health Sciences and Nutrition, Adelaide, Australia.
• Nina Holland, University of California, Berkeley, California, USA.
• Stefano Bonassi, National Cancer Institute, Genoa, Italy.

20³⁰-20³⁵

Michael Fenech: Overview of the achievements and goals of the HUMN project and the objectives of the Buccal MN Workshop. CSIRO Health Sciences and Nutrition, Adelaide, Australia.

20³⁵-21⁰⁰

Nina Holland: The use of buccal MN assay to study environmental and dietary genotoxic factors in young adults and children. University of California, Berkeley, USA.

21⁰⁰-21²⁵

Siegfried Knasmueller: Important effects of staining methods and scoring criteria on the observed result in the buccal MN assay. Institute of Cancer Research, Inner Medicine I, Medical University, Vienna, Austria.

21²⁵-21³⁵

Claudia Bolognesi: Demographic and exposure variables affecting buccal MN frequency in adults. National Cancer Research Institute, Genoa, Italy.

21³⁵-21⁴⁵

Sema Burgaz: Use of the buccal MN assay in genotoxin exposure studies in Turkey. Gazi University Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey.

21⁴⁵-22¹⁰

Stefano Bonassi: The use of statistical and epidemiological methods to identify methodological, demographic and exposure variables affecting MN frequency and its association with cancer risk. National Cancer Research Institute, Genoa, Italy.

22¹⁰-22³⁰

Open discussion on prospects and plans for an international collaborative study to harmonize and standardize the use of the buccal MN assay worldwide.

May 22^nd, Tuesday

08³⁰-09¹⁰

Keynote Lecture

Peter Briss

Improvement of public health, a national and international priority. 

Scientific Director, Coordinating Center for Environmental Health and Injury Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

(Introduction by William W. Au)

09¹⁰-09³⁰

Coffee Break

09³⁰-12⁰⁰

Symposium Session 4

Gene-Environmental Interactions on Health

(Sponsored by the National Institute of Environmental Health Sciences)

Co-Chairs:

• Douglas Bell, NIEHS, Research Triangle Park, NC, USA.
• Hannu Norppa, Finnish Institute of Occupational Health, Helsinki, Finland.

09³⁰-10⁰⁰

Peter Stambrook: Cellular mechanisms for preserving genomic integrity.  University of Cincinnati, Cincinnati, Ohio, USA.

10⁰⁰-10³⁰

Stefano Bonassi: Susceptibility and susceptible populations in environmental health - SNP’s, haplotypes, and exposure to asbestos in the etiology of Malignant Pleural Mesothelioma. National Cancer Research Institute, Genoa, Italy.

10³⁰-11⁰⁰

Hannu Norppa: Relationship between susceptibility, cytogenetic biomarkers and risk for development of cancer. Finnish Institute of Occupational Health, Helsinki, Finland.

11⁰⁰-11³⁰

Douglas Bell: Discovery and functional analysis of variation in human damage response pathway: p53 and NRF2. National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

11³⁰-12⁰⁰

Tom Kensler: Protection against cell injury through KEAP1-NRF2 signaling. Johns Hopkins University, Baltimore, MD, USA.

12⁰⁰-13⁰⁰

Lunch

13⁰⁰-15³⁰

Symposium Session 5

Translation of Scientific Knowledge into Public Health Practices

(Sponsored by the Joint Centers for Environmental Health and Injury Prevention, Centers for Disease Control and Prevention)

Co-Chairs:

• Christopher DeRosa, ATSDR, Atlanta, GA, USA.
• Rakhmet Bersimbaev, Kazakh National University, Almaty, Kazakhstan.

13⁰⁰-13³⁰

Peter Briss: Good science supports good decisions. Coordinating Center for Environmental Health and Injury Prevention, Atlanta, Georgia, USA.

13³⁰-14⁰⁰

Pamela Meyer: Global approach to reducing lead exposure and poisoning.  ATSDR, Atlanta, GA, USA.

14⁰⁰-14³⁰

Christopher DeRosa: Human health research and policy development in the Great Lakes.  ATSDR, Atlanta, Georgia, USA.

14³⁰-15⁰⁰

Takehiko Nohmi: DNA lesions and repair – asbestos and other environmental toxic chemicals. National Institute of Health Sciences, Tokyo, Japan.

15⁰⁰-15³⁰

Arthur Frank: Prevention of exposure to hazardous substances - social and ethical issues. Drexel University, Philadelphia, PA, USA.

15³⁰-15⁵⁰

Coffee Break

15⁵⁰-17¹⁰

Poster Session 1 (P-01 – P24)

17¹⁰-18⁴⁰

Workshop 2

Community Outreach and Health Promotion

(National Center for Environmental Health, and Agency for Toxic Substances and Disease Registry)

19⁰⁰

Dinner

May 23^th, Wednesday

08³⁰-11⁰⁰

Symposium Session 6

New Technologies and Frontiers in Environmental Health

Co-Chairs:

• Hikoya Hayatsu, Shijitsu University, Okayama, Japan.
• Malyn Chulasiri, Mahidol University, Bangkok, Thailand.

08³⁰-09⁰⁰

Hikoya Hayatsu: New technologies and concepts in genetic toxicology. Shijitsu Univ., Okayama, Japan.

09⁰⁰-09³⁰

Hiroshi Kasai: 4-Oxo-2-hexenal, a mutagen formed by ω-3 fat peroxidation: occurrence, detection and adduct formation. University Occupational and Environmental Health, Kitakyushu, Japan.

09³⁰-10⁰⁰

Leona Samson: Gene expression signatures predictive of prenatal arsenic exposure. Massachusetts Institute of Technology, Boston, USA.

10⁰⁰-10³⁰

Carole Yauk:  Germline mutation, DNA damage and epigenetic modification in response to exposure to particulate air pollution. Health Canada, Canada.

10³⁰-11⁰⁰

Jurgen Borlak:  The next innovation cycle in toxicogenomics . Frauenhofer Institute of Toxicol. Environ. Med., Germany.

11⁰⁰-11¹⁵

Coffee Break

11¹⁵-12⁴⁵

Poster Session 2 (P-25 – P-47)

12⁴⁵-13⁴⁵

Lunch

13⁴⁵-16¹⁵

Symposium Session 7

Unique Environmental Health Concerns and Consequences

Co-Chairs: